Sunday, February 23, 2020

HIS 117 - A Comparison of CASS: Cherokee, Anglo-Saxon and Saami societies


A Comparison of CASS: Cherokee, Anglo-Saxon and Saami societies

Melissa J. Dawson
Southern New Hampshire University
HIS-117-Q3149 World Civilizations to 1500





Introduction
            Societies can be viewed in a similar manner as biological entities. Just as an animal or plant adjusts to changing physical conditions around them, so do societies and civilizations adjust, evolve and cease to exist when outside pressures become too much. However, in that process they have formed a chain of societal norms that have responded to changing political, religious or ethical factors in order to become the societies we live in today. As such, there is value in learning more about these past iterations and what each group learned, did not heed and how they passed that shared historic memory on to us.
            Moving back through the centuries I believe the first groups were formed out of primal need. Need for extra hands to hunt down large game, a recognition of protection in numbers and a wider mating pool where more desired traits could be passed on to their offspring. Only once the primal and basic needs of food, shelter and sex were no longer in question, could humans begin to consider the more abstract things that form what we today consider essential for a functional society: Laws, Art, Music, Self-Expression, Spirituality and Science & Technology.
             I will be looking at the following three groups for further study and analysis: the Cherokee Nation Federations prior to contact with Europeans [Americas], Laplanders known as the Saami, in what is now Northern Finland, Sweden and Norway during the Iron Age [Northern Scandinavia], and the Anglo-Saxons prior to the Norman Conquest of 1066 [Europe]. I will be looking at the diversity of how dwellings and communities were structured and situated, as well as the evolving complex rules of law and societal norms each group developed.
            These three societies were chosen for specific, and personal, reasons. On my Father’s side I have a great-great-grandmother who was full Cherokee. Due to where the family was living in the 19th Century they were not part of the infamous Trail of Tears so therefore have maintained a longer continuity of experience. On my Mother’s side, both great-grandparents immigrated to the United States from Raahe, Finland. As such I have a great interest in many aspects of Finnish culture and traditions, including the Laplanders and the indigenous Saami people. And finally, I am a member of the Society for Creative Anachronism (SCA), my persona is based on a woman living just outside of Berwick, England in the 11th to 12th Century C.E. Yet the more I learn about the Anglos that controlled the trade and water routes in that area prior to the Battle of Hastings, the more interested I am in this society that was more technologically advanced and sophisticated than we have given them credit for in the past.
            These three examples, just like all other human created societies, states, and empires prior to 1500 C.E. were initially formed in order to maximize the ability to feed themselves and their families by distribution of the labor involved in collecting, preparing and preserving food resources during varying conditions and seasons.
Research and Analysis
            The Structure of Complex Societies
            During the Eleventh Century C.E. the global climate was still in a warming trend that would last another 200 years (Easterbrook, 2011). This meant that more Northern areas, such as Lapland, which covers the top quarter of Norway, Sweden and Finland were not as cold as they are today, leading to larger grazing lands for reindeer. Crops that would be difficult to grow in modern day England were cultivated by the Anglo-Saxons, such as grapes which in today’s climate would not thrive. Some of the Cherokee clans originally residing along the present-day US-Canadian border moved into the Southeast portion of the continent following the herds of deer that had wider range options (Cherokee Nation). For most humans who lived before 1500 C.E., one of the strongest driving forces of their daily lives was finding enough food to sustain themselves. Before the innovations of long-range weaponry or established domestication of food animals, the hunting and bringing down of an animal, or number of animals, large enough to feed a family or community was a very labor-intensive affair. And with little guarantee of success, there were real advantages to having a coalition of hunters assisting each other in this endeavor.
            As these migrations were taking place and different cultural groups moved into new lands, they brought with them, and had to create or adjust, the parameters of how living in settlements and community would function (The Anglo Saxons). When looking at where new societies settle the common factor is always a source of clean water. Water is vital for the survival of any community, even nomadic ones such as the Saami. Then the function(s) of each member of that society needs to be agreed upon and adhered to. Variations will always exist between groups based on cultural or religious norms, what is most important is that everyone follows the same set of rules, and that clear consequences are made known in response to the violation of that group’s norms, such as written by an Anglo-Saxon King (King Æthelberht’s Law Code).

A Sami family in front of a goahti in the foreground and a lavvu in the background (the picture is taken around 1900).
The Saami nomads of Lapland did not set up established communities or dwellings until the late 1800s, as with most nomadic groups their housing structures needed to be easily assembled, broken down, and transported from place to place (Kildahl, 2013). Their livelihood was intrinsically tied to the seasonal migration of their herds of reindeer along with spawning seasons of various fish, both fresh and salt water varieties.  As such their social structure was a Patriarchy headed up by
the eldest male of the household. Each Patriarch setting the rules for his household and dictating the limits of what the others were, or were not, allowed to do. Family units would come together at regular times to trade with other societies that wanted the fine furs and leathers made by the Saami, they were highly regarded and sought out for the quality of their goods (Demir, 2019).

Anglo-Saxon society was more established and structured even during the start of their emigration. They were primarily Germanic tribes who had crossed the Channel to take more productive lands and mineral resources for themselves on the main British Isle. Some had arrived prior to the onslaught of Viking raids along the East coast, others afterward. They brought with them established laws, a
court-system and settlement guidelines (Lambert, 2019). By the 11th Century C.E. the jockeying for power amongst the nobles had been resolved and they had settled into four distinct and powerful
kingdoms, of which only Essex would remain after the Norman Invasion of 1066 C.E. Danelaw and the system of reciprocity, which they called comitatus, were structuring the social standards of each Kingdom and village. These communities were deeply connected to the land, and of the three societies discussed in this paper, would be considered the wealthiest in terms of material items. They built more permanent structures, some in stone and many more of wood.

            The Cherokee of the Southeastern part of North America had a similar living arrangement that combined both seasonal nomadic groups along with established villages. Villages were situated at sections of a river that would offer not only food sources but a means of transportation between other settlements (Georgia Tribe of Eastern Cherokee). By the 11th Century C.E. they had not only a common language but long-standing sets of regulations and rules that governed punishment, the process for declaring war and agreed upon compensation options for a community
member that had been wronged. Similar to the Anglo-Saxons there were class stratifications that fell along the lines of skills and talents rather than just circumstances of birth. For example, the best hunters and trackers would follow migrating herds as they passed through the tribes’ territory to add to the community larder, while others would follow and prepare hides and meat for transport (Cherokee Nation). 
for transport (Cherokee Nation).
Class and Gender Structures
All three of the societies this paper looks at had very different sets of hard and fast regulations around the roles of men and women. The Cherokee did not sort their communities into class
structures based upon who your parents were as the Anglo-Saxon did. Instead your status within the village and larger tribe was based upon your own merit and efforts. If you showed an aptitude for herbalism and studied under the group’s shaman or healer, then it did not matter if your parents were merely tenders of a field. And for millennia, the Cherokee have been a Matriarchal Society, one of the few remaining such in the world today. When the early European settlers met with local men of the tribe and offered terms of working together or trade, they were shocked to be told that the men had to return and discuss the offer with their women before accepting. Women of the tribe control the majority of property and all children. When a woman marries it has to be from another village, to keep from introducing inbred issues. That husband then takes her family’s name and should they divorce he is ousted back to the village of his birth with only what he brought with

A reconstruction of an Anglo-Saxon woman based on a grave find in Dover dated to circa 575-625 AD. Dover Museum, Dover UK
 
him (History of American Women, 2018).
While not willing to give that much power to women, the Anglo-Saxon did acknowledge certain rights for women even within their carefully monitored class system. Rulers of kingdoms, villages and families were always men, and it was not likely that you could move up a class level from the one you were born into, so a peasant would not have the ability to become a free-holder or a soldier. Yet women were able to own land in their own names, assume the running of
a kingdom or business after the death of a father or husband, retained ownership of her own personal property and could not be forced into a marriage if she did not wish, this was regardless of your social status. Each class knew their place and their responsibilities. The Eoldorman expected martial service from the thanes and thanes in return expected the Lord to offer them protection (Lambert, 2019).
For the Saami the role of women carried some honor by virtue of being primary caretakers of children, passing on their culture and her skill in making clothing to protect her family during the brutal winters. However, this was a very patriarchal society with the father, or eldest male of a family group, making the decisions regarding who may marry, when they would move onto new lands and setting consequences for improper behavior as he saw fit. As technology was introduced to the Saami and clothing could be purchased, the role of the woman began to lose its importance, an issue that
modern-day Saami women are working to change (Andrews, 2019). Similar to most other nomadic cultures there is no defined class system, status in the great society is acquired based on the size of one’s herd or success in trade.




Intellectual and Religious Structures
            When they first arrived in England the Anglo-Saxons honored a variety of deities, similar to those the Celts and Picts in the area revered. Deities were associated with
specific events or phenomenon such as the changing of the seasons, a good harvest, protection in childbirth etc. However, around the 5th Century C.E. there began to be a widespread conversion to Christianity, so that by the 11th Century C.E. all four Kingdoms were officially Christian and a system of Priests,
Bishops and Monasteries had been established. Yet the traditional pagan feasts and festivals were still celebrated by most people in respect to their roots (Harrison, 2019). Gradually these became incorporated with Christian celebrations such as Easter. Similar to other European societies of the time the Anglo-Saxons were literate and kept copious written records about almost everything related to community life: deaths, baptisms, treaties and royal commands. Some of the best written records to survive from this period come from the venerable Bede, and English Benedictine monk (Bede, 731).
            The Saami never developed organized religious institutions, the ancient groups practiced a form of polytheism and animism. There is some archaeological evidence to suggest that early groups may have been influenced in part by their contact with Norse Vikings and their mythology. The belief system has a strong emphasis placed on the importance of personal spirituality along
with a deep connection to the natural and spiritual worlds (Mulk, 2008). The various offshoots of Saami that shared grazing lands each had its own distinct language originally, by the 12th Century C.E. many of these had blended into the ten recognized today, though three are considered on the verge of extinction. Their alphabet is loosely based on the Latin Vulgate characters with an addition of what we would see as Nordic adaptations, however they developed written language rather late in their cultural life (sometime in the 19th Century C.E.), and very little written records have survived due to a lack of safe or permanent storage – and the impermeability of the writing surfaces such as papyrus or hide (Kildahl, 2013). 
 

       Cherokee, as with almost all the North American tribe, practiced an oral tradition of history and culture for centuries. With each tribe having a specific language there were also some common languages that allowed Mohicans to communicate with the Saginaw and the Lakota with the Snoqualmish. Among all the Native American tribes the Cherokee were the first to have a standardized written language, but not until 1821 when Chief Sequoyah set it down (Library of Congress). Prior to that the history of a village or group was kept alive by the
Story Tellers who memorized all important events going back into the mists of time. There have also been discovered in Caves throughout the American Southeastern States, drawings and paintings that depict figures and animals. Not much is understood about their meaning as they have only begun to be studied in the last decade (Hunt, 2019). The Cherokee religion not only has deities for specific functions but they also believe that every living thing has a spirit and should be honored as such which is why they pray to that creature’s spirit before a hunt, or before felling a tree (Mails, 1992). 

Economic and Political Structures
            As mentioned previously each of these three civilizations did not live completely isolated and cut off from others around them. The Saami were well known in the Trading networks that sought skins, hides and furs for Southern markets, the Anglo-Saxons had a stellar reputation for their intricate gold-work – and the discovery of the Staffordshire Hoard highlighted their skill when it was unearthed in 2009. Cherokee villages would trade with other tribes who had access to items not within the tribe’s lands such as beads, ocean coastal shells or heavier furs like bear. Metal objects were also prized trade goods since the Native American tribes did not have the skill sets to forge their own. However, each had distinctly different forms of governmental systems.

       According to their official history the Cherokee’s first contact with Europeans was a meeting with the explorer Hernando DeSoto in 1540 (Cherokee.org). Regular contact with Europeans and exposure to their methods of government would not happen until the late 17th Century C.E. Where the Saami power player was the male head of a household, in Cherokee villages it
was a council of senior women and men who would discuss problems, trade offers and other events that would affect the group as a whole and come to a consensus as to the correct way to proceed. Cherokee society overall was organized into seven clans – clan affiliation determined who you could marry, your political alignment and was determined by who your mother was (Georgia Tribe).  Each village had two distinct units of government – the White Chief headed up a peacetime governing body and the Red Chief who ruled over a governing body during times of war. Medicine Chiefs were responsible to resolving disputes between the Red and White Chiefs.

            Prior to 1500 C.E., and European colonization, the Cherokee engaged in political battles, or war, over matters such as water rights and access or to protect hunting grounds and resources. Tribes traded with each other for items not readily accessible in their own territory or for specific goods. The Cherokee being known for their fine pottery pieces, just as others had acclaim for their weavings or decorative works (NCAI.org). Like the Saami, the Cherokee Nation today still maintains its own sovereignty within the modern political borders of another country – in this instance, the United States.  

As a people made up of small family groups that lived a nomadic existence following wild reindeer herds and migrating fish species, the Saami did not have any centralized or codified set of laws until their way of life changed in the 18th Century C.E.  (Ojala, 2009). At that time the ruling houses of the
Nordic region began to pay closer attention to the previously ignored frozen regions of their kingdoms and started levying taxes and enforcing boundary rules. This caused the Saami to convert to more sedentary breeders of domesticated reindeer. They did not have recognized autonomy as a unique culture and allowed to have self-rule until the late 19th – early 20th Century. As such they only have begun to form a united political and economic identity that their ancestors in the 11th Century C.E. did not need in order to support their families. This change over to sedentary animal raising also forced them to move from a bartering economy to one of coin and paper money – specific to the national borders they reside in today (Wallerström,  2000).

In direct contrast the Anglo-Saxon kingdoms were organized into a strict hierarchy, ultimately ruled by one king who had the final say in matters of State. Under the King were other members of the Royal Family, Nobility, Bishops, and other leaders of the Church. At the lowest rung were
slaves (Harrison, 2019). Writings from the 7th Century C.E. clearly capture the law-code of King Æthelberht of Kent, it outlines a complex system of punishment and compensation for infractions, based on the injured parties social standing and type of injury. For smaller arbitration matters such as a boundary dispute, the local Freeholder or Lord would be the definitive decision maker.

In terms of their economy, typical to most societies of that time it was primarily agriculture based with trade and barter being the main form of “currency”. Scheduled Markets were held for trade and the acquisition of exotic goods and spices from Asia, Northern Africa, Persia and the Mediterranean area. The regular market days were the places where coin money was utilized (GCSE, 2018).
Historical Perspective
When considering the influence Global Networks have had on specific cultures there can be seen both positive and negative after-effects. We are now aware that various societies had contact with each other much earlier than we believed just 20 years ago. Norse Vikings traded as far south as Spain, Northern Europeans with the money to spend would acquire goods from the Mediterranean Sea countries. Expansion of empires such as the Roman, Ottoman, Chinese Dynasties and the Catholic Church made the access to “exotic” items easier decade after decade (GCSE, 2018).
This is the positive side of the influence – commerce that increases market share and eventually lowers prices as goods become more commonly seen. Merchants can make a better living; more people are exposed to items used by counterparts thousands of miles away and local artisans are inspired to create replicas that open up newer markets for those in the middle and lower classes.
The down side however could be seen in the changing attitudes and appreciation for different cultures and places. Even just 100 years ago traveling outside your own territory or country meant that you would be exposed to different ways of dress, food, music and customs. That for me was the thrill of travel – the unknown and new. But with increased trade routes I wonder if some of the excitement of the “new” was jaded by having already seen, tasted or heard those things.
Conclusion
            These three examples, the Cherokee, Saami and Anglo-Saxon, just like all other human created societies, states, and empires prior to 1500 C.E. were formed in order to maximize the ability to feed themselves and their families by distribution of the labor involved in collecting, preparing and preserving food resources during varying conditions and seasons.
            For the Cherokee, the rise and fall of global empires did not affect them much at all. Prior to 1500 C.E. only a small handful of European explorers had set foot on North America’s landmass, and those were of small enough number to be viewed as a curiosity. When you consider the millions of Native Americans living on the continent, the number of those who died from exposure to a previously unknown pathogen, while tragic for the local groups, did not have much of a ripple effect on the much larger population. It would not be until the 17th Century C.E. when colonization began in earnest that their way of life would be really threatened.
            As nomadic family groups crossing the area known as Lapland, in a physical landscape that was being reclaimed by ice and snow, the Saami were not much affected by changing empires, even along their southern and eastern ranges. As they were inhabiting a place that had no appeal for whichever kingdom was claiming that land as part of their country, they were mostly left alone. The biggest change they probably saw was the ethnic make up of those non-Laplanders they traded with and the fluctuation of prices (Ojala, 2009). Even now the governments of Sweden, Norway and Finland all recognize them as a separate ethnic group and place their lands under protection in order to help them preserve this unique ethnic way of life.
            Not being safely isolated from the ongoing turmoil and changes in Europe, the Anglo-Saxons saw their final kingdom fall when the Normans invaded in 1066 C.E. In the aftermath their way of life, language and customs were quickly subsumed by another empire’s view of how things should be done. And during the 400 years to follow, one ethnic society after another were either assimilated into the current ruler’s paradigm, meaning that a lot of their beliefs and art were lost and never recorded. Some of it we are finding again thanks for archaeological digs, discovery of ancient texts and scholars who are diligently working to translate those texts. And what we are learning will forever change how we view those villages, kingdoms and empires that rose and fell before 1500 C.E. That contrary to what we may have been taught years ago – they were more sophisticated, technologically advanced and socially structured than previously thought. That far from being unwashed, illiterate scavengers living in caves or rickety built shelters they were more like us. Aside from the distance of years – they are us.













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PSY 300 Final Project: Biophysical & Biochemical Changes in Long-Term Disease States


 

 

 

 





Biophysical & Biochemical Changes in Long-Term Disease States
Melissa J. Dawson
Southern New Hampshire University
PSY 300 Biopsychology















Introduction
In prior classes I have read many articles about how a child’s brain and nervous system develop, what are standard behavior and action milestones, how do the hormones of puberty affect thought and emotions, the psychology of work, parenting and being a partner, the psychological effects of PTSD in Veterans and even discussions around how the median aging process affects perceptions and reactions. What I have struggled to find are academic and peer-reviewed studies on ways that facing personal mortality in combination with potential long-term medications for chronic conditions affect a person’s overall psychological make-up, which in term affects those around them.
            For example: What are the biochemical changes or triggers that occur in a cancer patient who has been exposed to a year of chemotherapy and has a prognosis of six months to live once they stop chemo versus a diabetic patient with failing kidneys who also has chosen to stop treatment such as dialysis. What affects the patient more keenly in their last months? The exposure to strong medications and treatments that are difficult physically – or the support of people around them, or the lack thereof. Can we show that specific drug therapies leave genome markers that can be linked to specific behavior and thought misalignments which could make the transition process more stressful or psychically more damaging than is necessary?
            Many patients diagnosed with progressive, long-term disease states are already being tested via bloodwork as a part of the general care management protocols. My proposed study would add peptides, hormones and proteins to the blood work done on patients with these chronic conditions. By comparing these levels in patients with the same diseases who are in hospice or palliative care researchers should be able to see which factors are different from the levels expressed in stable patients. Regular blood collections for many disease monitoring is not uncommon so patients will be used to the process. As any participant within hospice will only donate blood samples as they are comfortable doing so and may stop their participation at any time.

Literature Review – Article Summaries
Summary: They had postulated that brain tumor patients were more likely to underestimate the impairment to their psychological condition, including relationships, emotional states, cognitive function and impact on their carers. This was in comparison to other brain surgery patients with non-tumor patients. This was shown to be accurate after their data analysis was completed.

Summary: When adolescents self-medicate with alcohol there is enhanced dopamine neurotransmission which increases the user’s sense of wellbeing, which in turn tends to lead to larger and larger amounts of alcohol consumption to regain, or hold onto, the positive neural feedback they experience. And that the effect is most likely to become detrimental when started as teenagers as opposed to adulthood.

Summary: While this team was focused primarily on using neurophysiological testing methodologies to assess brain function, damage and potential for healing or ultimate decline, there are good possibilities to use this type of testing in other patient populations. We know that in military personnel with Traumatic Brain Injury (TBI), there can be changes in temperament, moods and cognitive functions. If these testing methods are able to detect disruptions in neural pathways and specific brain areas that are known to be linked to specific functions, the data could be calibrated to assess and treat other critically ill patients.

Artery Disease Patients: Associations with Thyroid Hormones, N-Terminal Pro-B-
Type Natriuretic Peptide and High-Sensitivity C-Reactive Protein. Archives of
Clinical Neuropsychology. 32(2). DOI: 10.1093/arclin/acx004
Summary: To determine whether biomarkers of health such as serum levels of free triiodothyronine (fT3), total triiodothyronine (TT3), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high-sensitivity C-reactive protein (hsCRP) impact the cognitive functioning of coronary artery disease (CAD) patients. The authors not that there does not seem to be any published studies to date that have looked at association between cognitive functioning and the hypothalamus-pituitary-thyroid ais in patients with CAD, they also note there are a dearth of studies looking at the axis and other long-term health conditions.

.           Summary: Congestive Heart Failure (CHF), as a result of Type 2 Diabetes, is an underlying cause of depression and cognitive dysfunction. A specific peptide (NT-proBNP) is a marker of CHF and patients with a rise in this peptide show a statistically significant risk factor for cognitive dysfunction.

Summary: Current state-of-the-art in hallucination studies does not warrant broad or uncritical use of this type of diagnosis in end-of-life care. Conclusions from interdisciplinary (as opposed to single discipline) hallucination studies suggest that the way forward for clinical and research work in palliative medicine may lie in a more biographical and cultural approach to unusual perceptions at the end of life. Researchers are looking at whether there are biochemical reasons for the accounts of hallucinations and visions in people who are dying.

Summary: The present study revealed key themes related to how patients come to terms with their impending death. Nurses are required to comprehend the patients’ complicated mental patterns that are expressed in their daily languages. Furthermore, the findings clarify the necessity for nurses to help patients understand the acceptance of a terminal disease state during a patient’s final days. A better understanding of the biochemical changes occurring in terminal patients can help caregivers better address cognitive decline in patients.

Literature Review – Summation of Changes and Relevance in the Field
            Within a book published in 1963 I found an interesting chapter outlining why the Greek philosopher Aristotle should be considered the father of Biopsychology (Kantor). It is apparent that Aristotle did postulate that within biological organisms, including man, there was a link between the psyche and the biological functions of the body:
“Metaproposition i. Psychological Events are Phases of biological Events. Inasmuch
as psyche is in some sense the principle of animal and plant life psychology must be
a special part of biology. It concerns the functions or acts of organisms as over against
their structure or organization, and their development or evolution.” (Kantor, pg 122)
However more current research has been able to show not just that there is correlation, but is now identifying specific neural pathways and the neural transmitters that regulate those pathways. The field has moved past the superstitions of the Middle Ages that labeled anyone with a mental disorder a witch or possessed. Past the Victorians and their belief that humors in the air were the cause of disease and any mental or personality disorder. Past a time where those with certain psychological malfunctions were locked up in institutions and subjected to a barrage of treatments and medications that often did more harm to the patient. And past the belief that willpower, a better diet or an herbal supplement are all you need to reverse any psychological condition.
Literature Review – Technology and Ethics
As technology within the medical sphere has evolved and become more sensitive to specific biologic functions, scientists are able to now “see” into the brain and the affected or responsive areas when a memory or other stimulus is introduced in the study subject. The field has moved past a carpet-bomb approach of medications which did little but sedate a patient to targeted hormone and neuroreceptor formulations that address only a specific misfunctioning structure. And moving forward the area of Deep Brain Stimulation (DBS) and externally applied electrical interventions show potential to re-wire misfiring neural centers without damaging large portions of the cerebral cortex as was seen in early use of shock therapy devices.  
Information shared between various medical disciplines has, and will continue, to aid researchers and practitioners in finding the most efficacious and least disruptive methods to help the person dealing with a psychological disorder. There have been limitations of course, especially as they relate to what is ethical by current standards. Prior to 1920 there seems to be little focus on whether any medical experimentation or research trial might be not just physically damaging to a participant, but emotionally and mentally as well. And while Science does owe gratitude to those who passed on structural and functional information about how the body works, their methods would be completely abhorrent to us if conducted today.
Modern clinical trials now focus on participant feedback, blood tests for antigens and neural receptors and external scanning such as MRI or CAT technology. In some ways this may be seen as slowing down the rate at which we are able to discover and learn, but societal norms insist that people are not lab rats and need to be treated with more care and dignity than they have experienced in the centuries past. Even lab rats are treated better today than human subject were just 200 years ago.
Research Design
Research Gap
As I mentioned in the introduction, my literature review was focused on looking at the data available which would identify any significant trends in current data that showed a causal relationship between ingested medications, or other chemical substances, and the expression of neural transmitters or hormones.
What are the biochemical changes or triggers that occur in a cancer patient who has been exposed to a year of chemotherapy (Chemo-brain, 2017) and has a prognosis of six months to live once they stop chemo versus a diabetic patient with failing kidneys who also has chosen to stop treatment such as dialysis. What affects the patient more keenly in their last months? The exposure to strong medications and treatments that are difficult physically – or the support of people around them, or the lack thereof (Azabou, 2017). Can we show that specific drug therapies leave genome markers that can be linked to specific behavior and thought misalignments which could make the transition process more stressful or psychically more damaging than is necessary?
Research Question
My research premise is:
Within the Hospice community there is a period of time for each patient when they are said to be “pre-actively dying” that refers to not a shutting down of the physical body which occurs in “active dying”, but a period of introspection and wanting to resolve unfinished inter-personal relationships. At the same time, their body and brain are reacting to the bio-chemical changes that chronic medication use or the disease itself are creating. Can we show that specific drug therapies or disease states leave genome markers that can be linked to specific behavior and thought misalignments which could make the transition process more difficult physically or psychologically more stressful than is necessary?
Research Design
            Proposed: A research protocol to monitor genomic markers, neurotransmitters and hormone levels in patients with a chronic illness receiving palliative care. The majority of patients receiving palliative care have had ongoing bloodwork done as part of their disease management. By comparing those samples with ongoing collection as their disease progresses researchers are looking to identify specific chemicals and concentrations that can be linked to changes in mood, cognition or personality. In addition to the blood analysis a trained researcher will collect data via a questionnaire format about how the patient perceived themselves psychologically before disease onset and how they perceive themselves currently. Care givers and close family or friends would also be invited to complete the questionnaire to give an objective view of the same. A control group of patients with the same disease states who are diagnosed as stable or in remission would also be asked the same questions and agree to a blood test at Day 1 and Day 120 to look for biomarker changes.
Research Ethics
            For robust data, cohorts should aim for 200-300 each. All participants will be randomized with no identifying information on either the samples of questionnaires, and the key to the randomization will be held at a separate location in a secure manner. Participants may elect to end their participation at any time for any reason. This will be a non-financially compensated study and participants informed that it will not provide any medical advantage or cure for them, but the information gathered could be used to help others with the same disease in the future. The Protocol will be reviewed by the Institutional Review Board (IRB) of the researcher’s primary institution as well as any Ethics Review Board or IRB of the patient’s primary doctor or palliative care facility.
            The field of Psychology has an unfortunate history of not always conducting studies to the highest possible standard of ethics, at least by today’s standards. Studies such as Project MKUltra, Stanford Prison Experiment, Baby Albert or the Pit of Despair would not be condoned, or allowed, under current guidelines. However, it may be said of current trials today that they crossed ethical lines when they are reviewed 100 years from now. The best researchers can do is to function not just within the Best Practices of any given field, but strive to rise a step above. For some people the idea of asking a person entering Hospice to participate in any clinical trial could be seen as ghoulish or unethical. Based on my experience with patients who are aware that their lifespan has been given a finite time frame, they arrive at a mental place where they are concerned about those around them in some ways more than they are for themselves. I think it would not be inappropriate to ask for their participation, or unethical, as I would not be promising them any personal or financial benefit. 
Research and Informed Ethics
            My understanding is that within this group of students, I am the only one with actual real-life experience working with a Clinical Trial team for Pharmaceutical or Medical Device companies. As such I have not only helped create Clinical Trial Protocols, but worked with the teams to train the clinical investigators, tracked IRB approvals, collected data, verified randomization and ensured no subject identifying data was present on those records. As part of my duties I attended company Ethics training every year along with re-training on Title 21 of the Code of Federal Regulations (21 CFR). There are specific sections that address the requirements for the Food and Drug Administration (FDA), the Drug Enforcement Agency (DEA) and the Office of National Drug Control Policy (ONDCP).
            I have participated in several FDA Audits, most which were routinely scheduled to assure the regulatory agency that our records were in compliance and there were no violations of law, regulations or ethics. I also experienced the type of audit no company wants to face – a surprise visit from a uniformed, and armed, FDA Auditor responding to serious failures of procedure. In the late 1990s I was part of a team working for American Home Products when our records were seized due to a court order by County Sheriffs as part of the fenfluramine / phentermine, usually called fen-phen, court case that arose from improper use of these drugs that resulted in the death of one women and hundreds of cases of serious cardiac disease.  
            So, my awareness of ethics in research along with medical and clinical trials is not the result of this course alone, or my current literature reviews. It was learned working side by side with Investigators, FDA Liaisons and one-the-job training. In fact, my view of bio-ethics are more narrowly focused than even some of my former colleagues who were willing to push the regulations “just a little” to save money on a larger and more costly study. I am not willing to fudge the regulations at all, I have seen the damage it can do to not only participants, but to a company or team who are trying to do the right thing and help people.
Being willing to shut down an experiment entirely, put it on hold or draft a significant re-write should not be something we take lightly, nor should these steps be set aside in order to meet an arbitrary deadline or budget. For what does it benefit Society as whole if a research team is exposed to pressure based on Investor expectations to cut corners and hold off on reporting serious adverse events just to complete a cohort? Or senior leadership ignores your progress notes telling them that documentation is not being properly completed and signed, which leaves us open to reprimand by regulatory agencies for not even following our own internal policies and procedures.
These are just a few of the actual occurrences I and my teams faced, which ultimately led me to leave the industry in search of a better way to make a positive difference in a patient’s life.

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Saturday, February 1, 2020

2020 SCA Birka Garb Challenge - Part 3

So ... Another Birka is in the books. I am constantly amazed at the range of creativity and talent seen in the range of Arts as well as everyday garb. But especially when it comes to the Garb Challenge. There were some truly amazing works.

But as this is MY page I am going to just focus on my outfit.

Here is a picture of my final outfit AND prop.





So here is some detailed information about the props.



I came up with the idea of having a tree in a pot come with me. in folklore the goddess Mielikki was married to an Oak Tree. Obviously, he would not be able to travel with me. So I noted to the audience that his "branch manager" was tasked to come with me. And yes, it is on wheels to roll with me.



On the tree are representatives of various forest animals such as bees, owls, squirrels, and a Norwegian Forest Cat. I also have a representative Orca along with two Guard Turtles and a local Lobster.













My thanks for Yona Carmichael for videotaping the various contestants. Here is my entry:








Monday, January 20, 2020

2020 SCA Birka Garb Challenge - Part 2

So Birka is this coming weekend and my garb is pretty much completed.







As this outfit was for a fantasy/mythology context I wanted to add an appropriate headdress. I found this headband with antlers at Savers as part of their Halloween costume offerins. I added glowers, fuit, vines and in the middle I attached a rubber otter.











I then turned to the overskirt. Last fall I had collected birch bark off a downed tree, then washed and pressed them. Using a translation program I took the goddess' name Meilliki and spelled it out in Runes. Then I traced the runes onto the birch bark and made applique piecess out of bark. These were appliqued down the right side of the apron. 




I added greenery and flowers to the bottom to highlight the connection this goddess has to the living and natural world.



This is the final decorated over apron dress. This was made from an old  wool Army blanket that came with the darker green stripe already woven into the material. it is merely cut to size and connected with pins at the shoulders to the matching back piece. I added additional chains, animal teeth and stones. Overall, this is one of the heaviest outfits I have ever made or worn.